技轉公告:纖維連接蛋白純化技術
創作人代表: 生化所 郭津岑老師
智慧財產權類型:專利(Patent)
中華民國專利
製備改良豬血漿纖連蛋白以增強傷口癒合之應用,專利號:I 674903
Process for a preparation of the modified porcine plasma fibronectin for enhance wound healing
美國專利(申請中)
PROCESS FOR A PREPARATION OF THE MODIFIED PORCINE PLASMA FIBRONECTIN FOR ENHANCE WOUND HEALING
美國專利(分割案申請中)
專利名稱:PROCESS FOR A PREPARATION OF THE MODIFIED PORCINE PLASMA FIBRONECTIN FOR ENHANCE WOUND HEALING
技轉方式:授權或讓與
技術內容摘要:
本發明揭示了可用於臨床傷口癒合與組織修復的材料及其應用。為了尋求安全的血漿纖連蛋白來源以使用於傷口敷料的實際應用,本發明從豬血漿中分離並修飾纖連蛋白,經修飾後的豬血漿纖連蛋白適用於人體,且可以作為刺激細胞貼附和定向細胞移動的基礎材料。本發明還揭示了一種增強傷口癒合的材料與一種醫藥組合物。
This invention reveals the potential applications of modified porcine plasma fibronectin that could be applied as a safe material for clinical wound healing and tissue repair. In order to seek safe sources of plasma fibronectin for practical consideration in wound dressing, this invention isolated and modified fibronectin from porcine plasma and demonstrated that modified porcine plasma fibronectin has similar ability as homo plasma fibronectin being as a suitable substrate for stimulation of cell adhesion and directed cell migration. The present invention also reveals a material and a pharmaceutical composition enhance wound healing.
本案聯絡人:徐猷凱管理師 02-28267398 ykhsu@nycu.edu.tw